Lupus triggers

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Lupus is a chronic (long-term) autoimmune disease.

9 out of 10 people with lupus are women.

Lupus symptoms can change over time and vary from person to person.

Symptoms can be:

Be light or heavy

Come and go

Lasts for a short or long time

Lupus flare-ups

Flare-ups or flare-ups occur when lupus symptoms worsen or a new symptom appears.

Symptoms of a flare-up may include:

  • Fever or flu-like symptoms that are not due to infection
  • Joint pain or swelling
  • fatigue
  • Rash, tingling or numbness
  • Sores or ulcers in the mouth or nose
  • Swelling in the legs

Lupus triggers

Common triggers that cause lupus symptoms for the first time or worsen existing symptoms include:

  • Sunlight and certain indoor light
    • Fluorescent or halogen bulbs
    • Ultraviolet (UV) rays from the sun or tanning beds
  • Medication
  • Some medications, such as hydralazine, procainamide, or quinidine, can cause drug-induced lupus.

  • Physical stress
    • Infections
    • Injuries
    • Big physical changes like pregnancy
  • Infections or diseases
    • Parvovirus
    • Herpes zoster
    • Epstein-Barr virus
    • Certain bacterial infections
  • Emotional stress
    • Care
    • Work stress
    • Financial concerns
    • Grief or loss
    • Discrimination and harassment

Childhood trauma and post-traumatic stress disorder (PTSD) are closely linked to lupus.

  • Exhaustion or lack of sleep
  • Air pollution
    • smoke
    • smog
    • Quartz dust, ozone and other particles
  • Exposure to heavy metals and toxins

Tracking your symptoms can help you recognize and avoid triggers and prevent lupus flare-ups.

This educational resource was created with support from Merck.

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