Chronic spontaneous urticaria 101

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October 1, 2025 is the world -uria day.

Urticaria is the medical word for hives – itchy red chairs that appear on her skin. Acute Urtikaria appears in response to an allergy or other source that you can identify, e.g. B. sunlight. The streaks usually disappear with time or treatment. But chronic spontaneous urticaria or CSU are hives that suddenly occur, last more than six weeks and, in contrast to acute urticaria, have no cause.

About 1% of people around the world get CSU. Most get it when they are in the 20s to 40s, even though they can get it at any age – even in childhood. Women get twice as likely as men, and black and not white people often get it as white people. A lower socio -economic status can also increase your chances for the CSU.

Bee sticks may seem harmless, but the constant, long -term itching from the registration can have a strong impact on their quality of life. And if you scratch you, you could be infected.

CSU symptoms

CSU gains may look like error bites, but there are differences. The hives:

  • Appear everywhere on the body, especially along the waist, under the arm and in the groin area
  • Change shapes
  • Disappear and reappear
  • Switch to different places
  • Look red or skin color
  • Wend white or disappear when you press them

If they scratched, they may also see scratches and blood.

CSU caused

In contrast to acute beehives, the cause of chronic hives is unknown. The researchers believe that half the time CSU is caused by an autoimmune problem, and their body sends histamine, which is a chemical that releases their body to combat allergies. Almost 1 out of 10 people with CSU have an autoimmune disease such as rheumatoid arthritis or type -1 diabetes.

If you have a CSU, you can find that some situations can make it worse, like if you are stressed or have an infection or if you are cold.

Diagnosis of CSU

Your health service provider (HCP) will determine whether you have acute urticaria or CSU. You will ask about a detailed medical history that searches for allergies or anything that could explain the hives. A physical examination is next, and looks at the beehives and where they are.

Blood tests do not diagnose CSU, but can exclude other causes and even look for autoimmune diseases if you suspect HCP that this could be the case.

Treat csu

Your HCP can refer you to an allergy sufferer, immunologist or dermatologist. The first treatment will probably be antihistamines (allergy medication). However, antihistamines are not effective for most people with CSU. If you don’t work, Omalizumab, which is also used for asthma, could be the next option, but many people are also not successful with omalizumab. A third option is cyclosporin that suppresses the immune system.

Researchers are also looking for alternative medication for people with CSU. In 2025, the Food and Drug Administration approved a biological medication called DuPilumab that controls the inflammation by blocking the immune system, and there are other biologics that are still in clinical studies. These drugs could be added to other treatments or help people who could not control their CSU with existing treatments.

This educational resource was created with the support of Sanofi, a healthy member of the corporate Advisory Council.

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