5 Chronic Conditions That Can Worsen an Overactive Bladder

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Do you have to run to the bathroom more often than usual during the day or wake up at night to go to the bathroom? Frequent urination can be more than just annoying and annoying. It can also be a sign of an underlying medical disorder.

An overactive bladder (OAB) can cause a sudden, urgent need to urinate that is difficult to control. You may feel the need to go to the bathroom even when your bladder is not full, causing you to go to the bathroom frequently.

The exact cause of OAB is not always clearly understood, and certain medical conditions or treatments may worsen urinary urgency, urinary frequency, nocturia, or other OAB-like symptoms.

While overactive bladder is more common in older adults, it is not considered a normal part of aging. Treatment may be helpful to relieve your symptoms and improve your quality of life.

Here are five medical conditions that can worsen or worsen OAB symptoms.

1. Cardiovascular diseases

Cardiovascular diseases, including high blood pressure, heart failure, and stroke, can worsen or worsen OAB. Reduced blood flow to the bladder (bladder ischemia) can lead to low oxygen levels in the bladder tissue, which can lead to nerve damage and muscle hypersensitivity.

Medications used to treat these diseases can also play an important role. Diuretics (“water pills”), commonly prescribed to control high blood pressure and heart failure, may increase urine output, potentially causing OAB-like frequency and urgency or worsening an existing overactive bladder. Other medications such as calcium channel blockers, β-blockers, and ACE inhibitors can also cause frequent urination.

2. Kidney disease

Chronic kidney disease (CKD) may be associated with changes in urination, including urinating more or less than normal, especially if kidney function changes.

Medications for CKD or for conditions such as high blood pressure and diabetes, including diuretics and SGLT2 inhibitors, can increase your body’s production of urine, potentially worsening OAB symptoms.

3. diabetes

Diabetes can significantly increase the risk of OAB. High blood sugar levels can cause diabetic neuropathies, which affect the nerves that control the bladder. Over time, nerve damage can cause a weak bladder to be unable to store or empty urine properly.

Too much glucose in the bloodstream can cause the kidneys to produce too much urine, increasing the urge and frequency of urination.

Some medications used to control diabetes, such as SGLT2 inhibitors and, in some cases, metformin, may also worsen OAB symptoms. For example, SGLT2 inhibitors can be used to flush excess glucose (sugar) and water into the urine, causing you to urinate more often.

5. Neurological disorders

Neurological diseases such as Parkinson’s disease, multiple sclerosis (MS), stroke, dementia, and spinal cord injuries can cause OAB-like symptoms of neurogenic bladder, a disorder of your bladder caused by nerve injury.

A neurogenic bladder occurs when an injury or disorder alters the electrical signals between the nervous system and the bladder. Stopping it can affect how the bladder stores or empties urine.

Depending on the specific condition, symptoms may include urgency, frequent urination, incontinence, or difficulty emptying the bladder.

Neurological disorders can affect bladder function:

  • The Parkinson’s disease It may increase urinary urgency, frequency, and nocturia (waking up two or more times per night to urinate).
  • The Multiple sclerosis (MS) It can damage the brain and spinal nerves and possibly cause spasms of the bladder muscles (detrusor overactivity).
  • Strokes may affect bladder control.
  • The dementia It can disrupt the connection between the brain and bladder and affect the perception of the need to urinate.
  • Spinal cord injuries You can completely change the bubble signals.

Some medications used to treat symptoms of neurological disorders, including anticholinergics, opioids, narcotics, antihistamines, and alpha-adrenergic agonists, may also aggravate or worsen bladder symptoms by affecting bladder emptying.

When to get help for an overactive bladder

If you think a medical condition or medication may be making your overactive bladder symptoms worse, contact your doctor. He or she may adjust your treatment plan or recommend additional medications to control your symptoms.

In addition to medications, some lifestyle changes may be helpful, such as:

  • Do Kegel exercises to strengthen your pelvic floor muscles
  • Limit foods and drinks that could irritate your bladder, such as: E.g. caffeinated drinks and lemonade
  • Control fluid consumption
  • Maintain a healthy weight
  • stop smoking
  • Use absorbent pads or protective underwear if necessary

This educational resource was created with the support of Sumitomo Pharma, Inc.

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